Stadium: Jack Coffey Field Round: 1
Home Manager: Joe Conlin Away Manager: Bob Chesney
| NCAAF | 2021/03/27 17:00 | Fordham v Holy Cross | W | 24-34 |
| NCAAF | 2019/11/16 18:00 | Holy Cross v Fordham | W | 49-27 |
| NCAAF FCS | 2018/11/10 17:05 | Fordham v Holy Cross | W | 13-17 |
| NCAAF | 2017/11/04 17:00 | Fordham v Holy Cross | W | 20-42 |
| NCAAF | 2021/11/06 16:30 | Lafayette v Holy Cross | W | 10-35 |
| NCAAF | 2021/10/30 16:00 | Holy Cross v Lehigh | W | 31-12 |
| NCAAF | 2021/10/23 21:00 | Colgate v Holy Cross | W | 10-42 |
| NCAAF | 2021/10/16 17:30 | Georgetown v Holy Cross | W | 14-48 |
| NCAAF | 2021/10/02 17:30 | Harvard v Holy Cross | L | 38-13 |
| NCAAF | 2021/09/25 17:00 | Holy Cross v Monmouth | W | 45-15 |
| NCAAF | 2021/09/18 16:00 | Holy Cross v Yale | W | 20-17 |
| NCAAF | 2021/09/11 18:00 | Merrimack v Holy Cross | L | 35-21 |
| NCAAF | 2021/11/06 16:30 | Fordham v Georgetown | W | 41-20 |
| NCAAF | 2021/10/23 17:00 | Lehigh v Fordham | W | 28-35 |
| NCAAF | 2021/10/16 17:00 | Bucknell v Fordham | W | 21-66 |
| NCAAF | 2021/10/09 17:00 | Wagner v Fordham | W | 7-56 |
| NCAAF | 2021/10/02 19:30 | Fordham v Lafayette | W | 42-41 |
| NCAAF | 2021/09/25 19:30 | Fordham v Stony Brook | W | 31-14 |
| NCAAF | 2021/09/18 22:00 | Fordham v Florida Atlantic | L | 14-45 |
| NCAAF | 2021/09/11 22:00 | Monmouth v Fordham | L | 26-23 |