Stadium: Joseph J. Gentile Center
Home Manager: Kate Achter Away Manager:
| WNCAAB | 2021/11/20 18:00 | Chicago State - Dames v Loyola Chicago - Dames | W | 59-71 |
| WNCAAB | 2021/11/18 01:00 | Loyola Chicago - Dames v Northwestern - Dames | L | 47-63 |
| WNCAAB | 2021/11/13 01:00 | Loyola Chicago - Dames v DePaul - Dames | L | 53-87 |
| WNCAAB | 2021/11/09 22:00 | Detroit - Dames v Loyola Chicago - Dames | W | 40-63 |
| WNCAAB | 2021/03/21 16:00 | Abilene Christian - Dames v Loyola Chicago - Dames | W | 55-74 |
| WNCAAB | 2021/03/20 16:00 | Manhattan - Dames v Loyola Chicago - Dames | L | 56-51 |
| WNCAAB | 2021/03/19 18:30 | Loyola Chicago - Dames v Stetson - Dames | L | 45-49 |
| WNCAAB | 2021/03/14 00:00 | Loyola Chicago - Dames v Bradley - Dames | L | 56-70 |