Stadium: Neta and Eddie DeRose ThunderBowl Round: 1
| NCAAF | 2022/09/03 23:00 | Midwestern State University Mustangs v Colorado State Pueblo Thunderwolves | W | 27-59 |
| NCAAF | 2022/11/19 19:00 | Colorado School of Mines v Colorado State Pueblo Thunderwolves | L | 45-24 |
| NCAAF | 2022/11/12 19:00 | Black Hills State Yellow Jackets v Colorado State Pueblo Thunderwolves | W | 0-38 |
| NCAAF | 2022/11/05 20:00 | Colorado State Pueblo Thunderwolves v South Dakota Mines Hardrockers | W | 45-20 |
| NCAAF | 2022/10/29 19:00 | Colorado Mesa University Mavericks v Colorado State Pueblo Thunderwolves | W | 28-33 |
| NCAAF | 2022/10/22 20:00 | Colorado State Pueblo Thunderwolves v Chadron State Eagles | W | 34-12 |
| NCAAF | 2022/10/15 20:00 | Colorado State Pueblo Thunderwolves v N. Mexico H. Cowboys | W | 35-11 |
| NCAAF | 2022/10/08 19:00 | Adams State Grizzlies v Colorado State Pueblo Thunderwolves | W | 20-52 |
| NCAAF | 2022/10/01 20:00 | Colorado State Pueblo Thunderwolves v Fort Lewis Skyhawks | W | 75-3 |
| NCAAF | 2022/11/12 19:00 | Midwestern State University Mustangs v Angelo State Univeristy Rams | L | 19-37 |
| NCAAF | 2022/11/06 00:00 | Texas AM Kingsville Javelinas v Midwestern State University Mustangs | W | 37-41 |
| NCAAF | 2022/10/30 00:00 | Midwestern State University Mustangs v Western Oregon | W | 26-21 |
| NCAAF | 2022/10/22 23:00 | Texas-Permian Basin Falcons v Midwestern State University Mustangs | W | 23-24 |
| NCAAF | 2022/10/16 01:00 | Central Washington University Wildcats v Midwestern State University Mustangs | L | 17-10 |
| NCAAF | 2022/10/09 00:00 | Midwestern State University Mustangs v West Texas AM Buffaloes | L | 26-38 |
| NCAAF | 2022/10/02 00:00 | Western New Mexico Mustangs v Midwestern State University Mustangs | L | 30-27 |
| NCAAF | 2022/09/25 00:00 | Midwestern State University Mustangs v Simon Fraser Clan | W | 77-0 |