Stadium: Saluki Stadium Round: 1
Home Manager: Nick Hill Away Manager: Ryan Beard
| NCAAF | 2022/10/08 19:00 | SO Illinois v Missouri St | L | 38-21 |
| NCAAF | 2021/11/06 17:00 | Missouri St v SO Illinois | W | 38-28 |
| NCAAF | 2021/03/27 19:00 | SO Illinois v Missouri St | W | 27-30 |
| NCAAF | 2019/11/09 20:00 | Missouri St v SO Illinois | L | 14-37 |
| NCAAF | 2018/10/27 19:00 | Missouri St v SO Illinois | L | 35-49 |
| NCAAF | 2017/11/04 18:00 | SO Illinois v Missouri St | W | 28-36 |